Article
Effect of p53 polymorphism on the susceptibility of cervical cancer.
Gynecologic and obstetric investigation - 1 Jan 2001
Yang Y C, Chang C L, Chen M L
Abstract excerpt
Using PCR amplification followed by confirmation with BstU I restriction enzyme digestion, the p53 Pro sequence was determined in tissues from 88 normal cervices, in 184 cervical swabs with mildly abnormal Pap smear, in 50 squamous cell cervical carcinoma specimens, and in 30 cervical adenocarcinoma samples. The frequencies for homozygous proline (Pro-72), homozygous arginine (Arg-72), and heterozygous...
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