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Article

Fatty aldehyde dehydrogenase: genomic structure, expression and mutation analysis in Sjögren-Larsson syndrome.

Chemico-biological interactions - 30 Jan 2001

Rizzo W B, Lin Z, Carney G

Abstract excerpt

Fatty aldehyde dehydrogenase (FALDH) is a microsomal enzyme that catalyzes the oxidation of medium- and long-chain aliphatic aldehydes derived from metabolism of fatty alcohol, phytanic acid, ether glycerolipids and leukotriene B4. The FALDH gene (ALDH3A2) in man and mouse consists of 11 exons and is closely linked to the gene for ALDH3. In both species, alternative splicing results in formation of a second minor...

Topics

Aldehyde Oxidoreductases
Amino Acid Sequence
Animals
Gene Expression
Humans
Mice
Molecular Sequence Data
Mutation
Mutation, Missense
Polymorphism, Genetic
Sequence Homology, Amino Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sjogren-Larsson Syndrome

Species Specificity

Source

Identifiers

PMID: 11306053
DOI: 10.1016/s0009-2797(00)00273-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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