Article
Molecular spectrum of beta-thalassemia in the Iranian Province of Hormozgan.
Hemoglobin - 1 Feb 2001
Yavarian M, Harteveld C L, Batelaan D, Bernini L F, Giordano P C
Abstract excerpt
Prevention of beta-thalassemia implies knowledge of the molecular spectrum occurring in the population at risk. This knowledge is necessary, especially when a prevention protocol is applied to a multiethnic population. For this purpose, we have recently analyzed a large population of Iranian patients living in the Province of Hormozgan in Iran, and a small group of Iranian patients living in The Netherlands. We...
Topics
- 5' Untranslated Regions
- Alleles
- Amino Acid Substitution
- Cluster Analysis
- DNA Mutational Analysis
- Ethnicity
- Gene Frequency
- Genetic Carrier Screening
- Genotype
- Globins
- Humans
- Iran
- Mutation, Missense
- Netherlands
- Polymerase Chain Reaction
- Sequence Deletion
- beta-Thalassemia