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Article

A novel heterodimeric antimicrobial peptide from the tree‐frog <i>Phyllomedusa distincta</i>

4 Apr 2001

Abstract excerpt

We present here the purification and the analysis of the structural and functional properties of distinctin, a 5.4 kDa heterodimeric peptide with antimicrobial activity from the tree-frog Phyllomedusa distincta. This peptide was isolated from the crude extract of skin granular glands by different chromatographic steps. Its minimal inhibitory concentration was determined against pathogenic Escherichia coli,...

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PMID: 11297740
DOI: 10.1016/s0014-5793(01)02324-9

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