Article
HLA diversity, differentiation, and haplotype evolution in Mesoamerican Natives.
Human immunology - 1 Apr 2001
Hollenbach J A, Thomson G, Cao K, Fernandez-Vina M, Erlich H A, Bugawan T L, Winkler C, Winter M, Klitz W
Abstract excerpt
Genetic variation of the Human Leukocyte Antigen region (HLA) in three Amerindian populations from the Southern Mexican state of Oaxaca, the Zapotec, Mixtec and the Mixe is examined. Individuals were typed using PCR-SSOP for four class II loci (DRB1, DQA1, DQB1, DPB1) and three class I loci (HLA-A, -B, and -C). Based on known HLA distributions, European admixture ranged from 1% to 10%. Individuals with European...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.