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Article

Features of the 3'-consensus sequence of rotavirus mRNAs critical to minus strand synthesis.

Virology - 10 Apr 2001

Chen D, Barros M, Spencer E, Patton J T

Abstract excerpt

The last seven nucleotides of the 3'-end of rotavirus mRNAs, 5'-UGUGACC-3', are highly conserved and form a cis-acting signal that can promote the synthesis of (-) strand RNA to produce the viral dsRNA genome in vitro. Previous studies have shown that the sequence, location, and strandedness (single- versus double-stranded) of the 3'-consensus sequence of the mRNA affect the efficiency of (-) strand synthesis. In...

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Identifiers

PMID: 11289804
DOI: 10.1006/viro.2001.0825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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