Article
Features of the 3'-consensus sequence of rotavirus mRNAs critical to minus strand synthesis.
Virology - 10 Apr 2001
Chen D, Barros M, Spencer E, Patton J T
Abstract excerpt
The last seven nucleotides of the 3'-end of rotavirus mRNAs, 5'-UGUGACC-3', are highly conserved and form a cis-acting signal that can promote the synthesis of (-) strand RNA to produce the viral dsRNA genome in vitro. Previous studies have shown that the sequence, location, and strandedness (sin...
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