Article
Mutations of rubella virus vaccine TO-336 strain occurred in the attenuation process of wild progenitor virus.
Vaccine - 6 Apr 2001
Kakizawa J, Nitta Y, Yamashita T, Ushijima H, Katow S
Abstract excerpt
The sequences of the genomes in the TO-336 vaccine strain (TO-336vac) of rubella virus and its wild progenitor virus (TO-336wt) have been determined and compared with each other. There were 21 differences in the nucleotide sequences between the TO-336vac and the TO-336wt: 13 in the nonstructural...
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