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Article

Identification of Strain-Specific Nucleotide Sequences in the RA 27/3 Rubella Virus Vaccine

1 Oct 1993

Abstract excerpt

A polymerase chain reaction-based protocol was developed for determination of the sequence of 1300 nucleotides in the E1 coding region of the genomes of multiple strains of rubella virus. From a collection of sequences of 9 independent strains and isolates, characteristic nucleotides were identified that distinguished the RA 27/3 strain, which is the currently used attenuated vaccine strain. These characteristic...

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PMID: 8376831
DOI: 10.1093/infdis/168.4.854

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