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Article

Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway.

The Journal of biological chemistry - 27 Apr 2001

Gamero A M, Larner A C

Abstract excerpt

Type I interferon (IFN)-dependent inhibition of cell growth can occur either in the absence or presence of apoptosis. The mechanisms that determine whether or not cells undergo apoptosis after exposure to IFN-alpha are not clear. This study shows that a variety of cell lines that display growth inhibition but not apoptosis in response to IFN-alpha will undergo programmed cell death when low concentrations of the...

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Identifiers

PMID: 11278370
DOI: 10.1074/jbc.M007948200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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