Article
Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification.
International journal of cancer - 1 Mar 2001
Plantaz D, Vandesompele J, Van Roy N, Lastowska M, Bown N, Combaret V, Favrot M C, Delattre O, Michon J, Bénard J, Hartmann O, Nicholson J C, Ross F M, Brinkschmidt C, Laureys G, Caron H, Matthay K K, Feuerstein B G, Speleman F
Abstract excerpt
We have studied the occurrence and association of 11q deletions with other chromosomal imbalances in Stage 4 neuroblastomas. To this purpose we have performed comparative genomic hybridization (CGH) analysis on 50 Stage 4 neuroblastomas and these data were analyzed together with those from 33 previously published cases. We observed a high incidence of 11q deletion in Stage 4 neuroblastoma without MYCN...
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