Article
Environmental health and genomics: visions and implications.
Nature reviews. Genetics - 1 Nov 2000
Olden K, Wilson S
Abstract excerpt
The relationship between genes and the environment can be compared to a loaded gun and its trigger. A loaded gun by itself causes no harm; it is only when the trigger is pulled that the potential for harm is released. Genetic susceptibility creates an analogous situation, where the loaded gun is one or a combination of susceptibility genes (alleles) and the trigger is an environmental exposure. The key objective...
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