Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCR

1 Sept 2003

Abstract excerpt

Molecular techniques have been developed for prenatal diagnosis of the most common chromosome disorders (trisomies 21, 13, 18 and sex chromosome aneuploidies) where results are available within a day or two. This involves fluorescence in situ hybridization (FISH) and microscopy analysis of fetal cells or quantitative fluorescence polymerase chain reaction (QF-PCR) on fetal DNA. Guidance is provided on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal and Genetic Variations
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12968936
DOI: 10.1530/rep.0.1260279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCRPMID 12968936Read ↗

Rapid prenatal diagnosis of common chromosome aneuploidies by QF‐PCR, results of 9 years of clinical experienceSemantic proximity Read ↗

The introduction of QF-PCR in prenatal diagnosis of fetal aneuploidies: time for reconsiderationSemantic proximity Read ↗

International, collaborative assessment of 146 000 prenatal karyotypes: expected limitations if only chromosome-specific probes and fluorescent in-situ hybridization are usedSemantic proximity Read ↗

Rapid prenatal diagnosis of common chromosome aneuploidies by QF-PCR. Assessment on 18 000 consecutive clinical samplesSemantic proximity Read ↗

Rapid prenatal diagnosis of aneuploidy by quantitative fluorescent PCR on fetal samples from mothers at high risk for chromosome disordersSemantic proximity Read ↗

Rapid detection of aneuploidies by microsatellite and the quantitative fluorescent polymerase chain reactionSemantic proximity Read ↗

Rapid Prenatal Diagnosis of Aneuploidy Using Quantitative Fluorescence-PCR (QF-PCR)Semantic proximity Read ↗

An assessment of the use of interphase FISH with chromosome specific probes as an alternative to cytogenetics in prenatal diagnosisSemantic proximity Read ↗

Prenatal diagnosis of common aneuploidies using quantitative fluorescent PCRSemantic proximity Read ↗

Antenatal screening for chromosomal abnormalitiesSemantic proximity Read ↗

Prenatal detection of chromosome aneuploidy by quantitative-fluorescence PCR.Semantic proximity Read ↗

Molecular cytogenetic and rapid aneuploidy detection methods in prenatal diagnosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.