Article
Axonemal beta heavy chain dynein DNAH9: cDNA sequence, genomic structure, and investigation of its role in primary ciliary dyskinesia.
Genomics - 15 Feb 2001
Bartoloni L, Blouin J L, Maiti A K, Sainsbury A, Rossier C, Gehrig C, She J X, Marron M P, Lander E S, Meeks M, Chung E, Armengot M, Jorissen M, Scott H S, Delozier-Blanchet C D, Gardiner R M, Antonarakis S E
Abstract excerpt
Dyneins are multisubunit protein complexes that couple ATPase activity with conformational changes. They are involved in the cytoplasmatic movement of organelles (cytoplasmic dyneins) and the bending of cilia and flagella (axonemal dyneins). Here we present the first complete cDNA and genomic sequences of a human axonemal dynein beta heavy chain gene, DNAH9, which maps to 17p12. The 14-kb-long cDNA is divided...
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