Article
Sequence variations in the amino- and carboxy-terminal parts of the surface envelope glycoprotein of HTLV type 1 induce specific neutralizing antibodies.
AIDS research and human retroviruses - 1 Mar 2001
Tallet B, Astier-Gin T, Moynet D, Londos-Gagliardi D, Guillemain B
Abstract excerpt
The surface envelope glycoprotein gp46 of the human T cell leukemia virus type 1 elicits a strong immune response. Its protective role against HTLV-1 infection in animal models is well established, suggesting that recombinant envelope glycoproteins or synthetic peptides could be used as an effective vaccine. However, reports have indicated that some variations in envelope sequences may induce incomplete...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
