Article
Clinical correlation of variations in the internal transcribed spacer regions of rRNA genes in Pneumocystis carinii f.sp. hominis.
AIDS (London, England) - 9 Mar 2001
Helweg-Larsen J, Lee C H, Jin S, Hsueh J Y, Benfield T L, Hansen J, Lundgren J D, Lundgren B
Abstract excerpt
OBJECTIVES: To analyse the importance of sequence variations in the internal transcribed spacer (ITS) regions 1 and 2 of the nuclear rRNA operon in AIDS patients with Pneumocystis carinii pneumonia (PCP). DESIGN AND METHODS: ITS 1 and 2 genotypes were determined in 162 bronchoalveolar lavage samples from 130 patients participating in a prospective cohort study of PCP. RESULTS: A total of 49 different ITS...
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