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Article

Characterization of a novel autosomal dominant bleeding disorder in a large kindred from east Texas.

Blood - 15 Mar 2001

Kuang S Q, Hasham S, Phillips M D, Wolf D, Wan Y, Thiagarajan P, Milewicz D M

Abstract excerpt

A large east Texas family with autosomal dominant inheritance of a novel bleeding disorder has been identified. The disorder is characterized clinically by easy bruising, life-threatening bleeding with trauma or surgery, and menorrhagia in affected women. Laboratory studies demonstrated prolongation of the prothrombin time and activated partial thromboplastin time in affected individuals. Paradoxically, assays of...

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PMID: 11238089
DOI: 10.1182/blood.v97.6.1549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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