Article
[Genetic factors in predisposition to bronchial asthma].
Genetika - 1 Jan 2001
Ivashchenko T E, Sideleva O G, Petrova M A, Gembitskaia T E, Orlov A V, Baranov V S
Abstract excerpt
The ratio between the normal (+) and null (0) alleles of the genes encoding glutatione S-transferases M1 (GSTM1) and T1 (GSTT1) were studied in normal individuals from northwestern Russia (control group) and in patients with bronchial asthma (BA). The frequency of the GSTM1 0/0 genotype in the population sample was statistically significantly lower (37.8%) than in the BA patients (82.1%; chi 2 = 16.8; P < 0.001;...
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