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Article

Cold adaptation of the thermophilic enzyme 3-isopropylmalate dehydrogenase.

Journal of biochemistry - 1 Mar 2001

Yasugi M, Amino M, Suzuki T, Oshima T, Yamagishi A

Abstract excerpt

We have performed random mutagenesis coupled with selection to isolate mutant enzymes with high catalytic activities at low temperature from thermophilic 3-isopropylmalate dehydrogenase (IPMDH) originally isolated from Thermus thermophilus. Five cold-adapted mutant IPMDHs with single-amino-acid s...

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Source

Identifiers

PMID: 11226889
DOI: 10.1093/oxfordjournals.jbchem.a002880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11226889-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Cold adaptation of the thermophilic enzyme 3-isopropylmalate dehydrogenase.PMID 11226889Read ↗

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