Article
Limitations of chromosome classification by multicolor karyotyping.
American journal of human genetics - 1 Apr 2001
Lee C, Gisselsson D, Jin C, Nordgren A, Ferguson D O, Blennow E, Fletcher J A, Morton C C
Abstract excerpt
Multicolor karyotyping technologies, such as spectral karyotyping (SKY) (Schröck et al.1996; Liyanage et al. 1996) and multiplex (M-) FISH (Speicher et al. 1996), have proved to be extremely useful in prenatal, postnatal, and cancer cytogenetics. However, these technologies have inherent limitations that, in certain situations, may result in chromosomal misclassification. In this report, we present nine cases,...
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