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Article

Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies?

Clinical neuropathology - 1 Jan 2000

Masullo C, Macchi G

Abstract excerpt

BACKGROUND: Human spongiform transmissible encephalopathies (TSE) are a group of neurodegenerative diseases caused by a transmissible not yet recognized agent; their distinctive neuropathological features are astrocytosis, spongiform lesions of the neuropil, neuronal loss and occasionally amyloid plaques in the cortical and subcortical gray matter. TSE are biochemically characterized by the deposition in the...

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PMID: 11220690

Genes

PRNP

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