Article
Molecular control of copper homeostasis in filamentous fungi: increased expression of a metallothionein gene during aging of Podospora anserina.
Molecular & general genetics : MGG - 1 Jan 2001
Averbeck N B, Borghouts C, Hamann A, Specke V, Osiewacz H D
Abstract excerpt
The lifespan of the ascomycete Podospora anserina was previously demonstrated to be significantly increased in a copper-uptake mutant, suggesting that copper is a potential stressor involved in degenerative processes. In order to determine whether changes in copper stress occur in the cells during normal aging of cultures, we cloned and characterized a gene coding for a component of the molecular machinery...
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