Article
At least one class I gene in restriction fragment pattern-Y (Rfp-Y), the second MHC gene cluster in the chicken, is transcribed, polymorphic, and shows divergent specialization in antigen binding region.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2001
Afanassieff M, Goto R M, Ha J, Sherman M A, Zhong L, Auffray C, Coudert F, Zoorob R, Miller M M
Abstract excerpt
MHC genes in the chicken are arranged into two genetically independent clusters located on the same chromosome. These are the classical B: system and restriction fragment pattern-Y (Rfp-Y), a second cluster of MHC genes identified recently through DNA hybridization. Because small numbers of MHC class I and class II genes are present in both B: and Rfp-Y, the two clusters might be the result of duplication of an...
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