Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activated Mitogenic Signaling Induces a Process of Dedifferentiation in Alzheimer's Disease That Eventually Results in Cell Death

1 Dec 2000

Abstract excerpt

Neurodegeneration in Alzheimer's disease (AD) is associated with the appearance of dystrophic neuronal growth profiles that most likely reflect an impairment of neuronal reorganization. This process of morphodysregulation, which eventually goes awry and becomes a disease itself, might be triggered either by a variety of life events that place an additional burden on the plastic capability of the brain or by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Microtubule and mitosis dynamics
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11193159
DOI: 10.1111/j.1749-6632.2000.tb06931.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activated Mitogenic Signaling Induces a Process of Dedifferentiation in Alzheimer's Disease That Eventually Results in Cell DeathPMID 11193159Read ↗

Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer diseaseSemantic proximity Read ↗

Neuronal cell cycle re-entry mediates Alzheimer disease-type changesSemantic proximity Read ↗

Alzheimer’s Disease and Cancer: When Two Monsters Cannot Be TogetherSemantic proximity Read ↗

MAPKs: new targets for neurodegenerationSemantic proximity Read ↗

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's diseaseSemantic proximity Read ↗

Review: Cell cycle aberrations and neurodegenerationSemantic proximity Read ↗

The Potential Role of Protein Kinase R as a Regulator of Age-Related NeurodegenerationSemantic proximity Read ↗

p53 at the crossroads between cancer and neurodegeneration.Semantic proximity Read ↗

p27, The Cell Cycle and Alzheimer´s DiseaseSemantic proximity Read ↗

The complex p25/Cdk5 kinase in neurofibrillary degeneration and neuronal death: The missing link to cell cycleSemantic proximity Read ↗

Dysregulated mTOR-dependent signaling in neurodegeneration or carcinogenesis: implication for Alzheimer's disease and brain tumors.Semantic proximity Read ↗

The Role of c-Abl Tyrosine Kinase in Brain and Its PathologiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.