Article
[Distribution of beta-thalassemia CD17 mutant(A-->T) in Shanxi, Gansu and Xinjiang along the "Silk Road"].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Oct 1998
Zhang Y, Yu W, Li H
Abstract excerpt
OBJECTIVE: To explore the distribution of beta-thalassemia CD17 mutant along the "Silk Road". METHOD: Polymerase chain reaction in combination with dot-blot hybridization of allele-specific oligonucleotide probes(PCR/ASO) was used. RESULTS: Twenty-four cases of beta-thalassemia with CD17 mutant(A-->T) including 3 cases in Shanxi, 20 cases in Gansu and 1 in Xinjiang, were found among 85 probands of...
Topics
- Adolescent
- Adult
- Alleles
- Antigens, CD
- Asian People
- Child
- China
- Female
- Gene Frequency
- Humans
- Male
- Middle Aged
- Point Mutation
- Polymerase Chain Reaction
- beta-Thalassemia