Article
Evaluation of DHPLC in the analysis of hemophilia A.
Journal of biochemical and biophysical methods - 30 Jan 2001
Oldenburg J, Ivaskevicius V, Rost S, Fregin A, White K, Holinski-Feder E, Müller C R, Weber B H
Abstract excerpt
The manifestation of hemophilia A, a common hereditary bleeding disorder in humans, is caused by abnormalities in the factor VIII (FVIII) gene. A wide range of different mutations has been identified and provides the genetic basis for the extensive variability observed in the clinical phenotype. The knowledge of a specific mutation is of great interest as this may facilitate genetic counseling and prediction of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.