Article
Involvement of acetyl phosphate in the in vivo activation of the response regulator ComA in Bacillus subtilis.
FEMS microbiology letters - 20 Feb 2001
Kim S B, Shin B S, Choi S K, Kim C K, Park S H
Abstract excerpt
Development of genetic competence in Bacillus subtilis is regulated by ComP--ComA, a two-component signal transduction system. The response regulator ComA is primarily activated by ComP, a histidine kinase that mediates response to nutrient conditions and cell density, and the activated ComA is required for transcription of the srf operon, which is essential for the development of genetic competence and surfactin...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Culture Media
- DNA-Binding Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Glucose
- Mutation
- Organophosphates
- Peptide Synthases
- Phosphate Acetyltransferase
- Phosphoproteins
- Phosphorylation
