Monozygotic twins of opposite sex.

doi:10.1159/000056859

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Article

Monozygotic twins of opposite sex.

Cytogenetics and cell genetics - 1 Jan 2000

Wachtel S S, Somkuti S G, Schinfeld J S

Abstract excerpt

Although discordant karyotypes are known in identical twins, cases involving differences in sex phenotype are rare. We studied identical twins with the 46,XY karyotype - a male with mixed gonadal dysgenesis and a female with "pure" gonadal dysgenesis. The testis-determining SRY gene was present in DNA from both twins but no mutations were detected in the SRY conserved motif. Monozygosity was indicated by short...

Topics

Adolescent
Conserved Sequence
DNA-Binding Proteins
Female
Gonadal Dysgenesis
Gonadal Dysgenesis, Mixed
Humans
Infant, Newborn
Male
Mosaicism
Mutation
Nuclear Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Penetrance

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Sex Characteristics

Sex Determination Processes

Sex Differentiation

Source

Open in PubMed

Identifiers

PMID: 11173871
DOI: 10.1159/000056859

Genes

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