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Article

The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.

Proceedings of the National Academy of Sciences of the United States of America - 13 Feb 2001

Helliwell C A, Chandler P M, Poole A, Dennis E S, Peacock W J

Abstract excerpt

We have shown that ent-kaurenoic acid oxidase, a member of the CYP88A subfamily of cytochrome P450 enzymes, catalyzes the three steps of the gibberellin biosynthetic pathway from ent-kaurenoic acid to GA(12). A gibberellin-responsive barley mutant, grd5, accumulates ent-kaurenoic acid in developing grains. Three independent grd5 mutants contain mutations in a gene encoding a member of the CYP88A subfamily of...

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Identifiers

PMID: 11172076
DOI: 10.1073/pnas.98.4.2065
PMCID: PMC29382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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