Article
Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6.
Development (Cambridge, England) - 1 Mar 2001
Bürglin T R, Ruvkun G
Abstract excerpt
Caenorhabditis elegans has three POU homeobox genes, unc-86, ceh-6 and ceh-18. ceh-6 is the ortholog of vertebrate Brn1, Brn2, SCIP/Oct6 and Brn4 and fly Cf1a/drifter/ventral veinless. Comparison of C. elegans and C. briggsae CEH-6 shows that it is highly conserved. C. elegans has only three POU homeobox genes, while Drosophila has five that fall into four families. Immunofluorescent detection of the CEH-6...
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