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Article

Evolution of the mitochondrial genetic system: an overview.

Gene - 30 Dec 2000

Saccone C, Gissi C, Lanave C, Larizza A, Pesole G, Reyes A

Abstract excerpt

Mitochondria, semi-autonomous organelles possessing their own genetic system, are commonly accepted to descend from free-living eubacteria, namely hydrogen-producing alpha-proteobacteria. The progressive loss of genes from the primitive eubacterium to the nucleus of the eukaryotic cell is strongly justified by the Muller rachet principle, which postulates that asexual genomes, like mitochondrial ones, accumulate...

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PMID: 11164046
DOI: 10.1016/s0378-1119(00)00484-4

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