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The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix.

Molecular and cellular biology - 1 Feb 2001

Prohl C, Pelzer W, Diekert K, Kmita H, Bedekovics T, Kispal G, Lill R

Abstract excerpt

The transport of metabolites, coenzymes, and ions across the mitochondrial inner membrane is still poorly understood. In most cases, membrane transport is facilitated by the so-called mitochondrial carrier proteins. The yeast Saccharomyces cerevisiae contains 35 members of the carrier family, but a function has been identified for only 13 proteins. Here, we investigated the yeast carrier Leu5p (encoded by the...

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Identifiers

PMID: 11158296
DOI: 10.1128/MCB.21.4.1089-1097.2001
PMCID: PMC99563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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