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Article

Influence of smoking, hypertension, and sex on the phenotypic expression of familial intracranial aneurysms in siblings.

Neurosurgery - 1 Jan 2001

Connolly E S, Choudhri T F, Mack W J, Mocco J, Spinks T J, Slosberg J, Lin T, Huang J, Solomon R A

Abstract excerpt

OBJECTIVE: To investigate the effects of smoking, hypertension, and sex on the phenotypic expression of familial intracranial aneurysms (FIAs). METHODS: We retrospectively reviewed the case records of 806 consecutive patients undergoing aneurysm surgery at our institution (1986-1995) and discovered 24 families with at least two affected siblings. Prevalence rates for the smoking, hypertension, and sex risk...

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Identifiers

PMID: 11152362
DOI: 10.1097/00006123-200101000-00011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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