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Article

Long-term live imaging reveals cytosolic immune responses of host hepatocytes against <i>Plasmodium</i> infection and parasite escape mechanisms

24 Jul 2015

Abstract excerpt

Plasmodium parasites are transmitted by Anopheles mosquitoes to the mammalian host and actively infect hepatocytes after passive transport in the bloodstream to the liver. In their target host hepatocyte, parasites reside within a parasitophorous vacuole (PV). In the present study it was shown that the parasitophorous vacuole membrane (PVM) can be targeted by autophagy marker proteins LC3, ubiquitin, and...

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PMID: 26208778
DOI: 10.1080/15548627.2015.1067361

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