Article
The parkinsonian models: invertebrates to mammals.
Japanese journal of pharmacology - 1 Nov 2000
Kitamura Y, Shimohama S, Akaike A, Taniguchi T
Abstract excerpt
In contrast to Alzheimer's disease, effective therapeutic options are available for Parkinson's disease. Therapy of dopamine replacement such as levodopa improves the symptoms of this disease, but does not inhibit neurodegeneration in the substantia nigra. Numerous studies have suggested that endogenous and environmental neurotoxins, and oxidative stress may participate in this disease, but the detailed...
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