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Article

Altered frequency of a promoter polymorphism of the kinin B2 receptor gene in hypertensive African-Americans

1 Dec 2000

Abstract excerpt

Components of the kallikrein kinin system have been associated with the pathophysiology of hypertension in animal and human studies. In this study, we examined the distribution of four different polymorphisms of the kinin B1 and B2 receptor genes in a population of 120 normotensive and 77 hypertensive African-Americans. Allelic frequencies for three of the four polymorphisms were significantly different from...

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PMID: 11130770
DOI: 10.1016/s0895-7061(00)01215-2

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