Article
Osa-containing Brahma chromatin remodeling complexes are required for the repression of wingless target genes.
Genes & development - 15 Dec 2000
Collins R T, Treisman J E
Abstract excerpt
The Wingless signaling pathway directs many developmental processes in Drosophila by regulating the expression of specific downstream target genes. We report here that the product of the trithorax group gene osa is required to repress such genes in the absence of the Wingless signal. The Wingless-regulated genes nubbin, Distal-less, and decapentaplegic and a minimal enhancer from the Ultrabithorax gene are...
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