Article
The spineless-aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila.
Development (Cambridge, England) - 1 Sept 1999
Emmons R B, Duncan D, Estes P A, Kiefel P, Mosher J T, Sonnenfeld M, Ward M P, Duncan I, Crews S T
Abstract excerpt
The Drosophila spineless (ss) gene encodes a basic-helix-loop-helix-PAS transcription factor that is required for proper specification of distal antennal identity, establishment of the tarsal regions of the legs, and normal bristle growth. ss is the closest known homolog of the mammalian aryl hydrocarbon receptor (Ahr), also known as the dioxin receptor. Dioxin and other aryl hydrocarbons bind to the PAS domain...
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