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Cerebral malaria and immunogenetics

1 Dec 2000

Abstract excerpt

Cerebral malaria depends largely on the capacity of Plasmodium falciparum infected red blood cells to adhere to the endothelia of microvessels, leading to their occlusion. The most important players include receptors expressed on the surface of the endothelial cell and known to interact with the parasite, cytokines modulating the expression of these adhesion molecules and nitric oxide (NO). Platelets, monocytes...

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PMID: 11123753
DOI: 10.1046/j.1365-3024.2000.00342.x

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