Article
Familial aggregation of psychotic symptoms in Huntington's disease.
The American journal of psychiatry - 1 Dec 2000
Tsuang D, Almqvist E W, Lipe H, Strgar F, DiGiacomo L, Hoff D, Eugenio C, Hayden M R, Bird T D
Abstract excerpt
OBJECTIVE: The mutation responsible for Huntington's disease is an elongated and unstable trinucleotide (CAG) repeat on the short arm of chromosome 4. Psychotic symptoms are more common in patients with Huntington's disease than in the general population. This study explored the relationship of psychosis in Huntington's disease patients with the number of CAG repeats and family history of psychosis. METHOD:...
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