Article
Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI.
Hepatology (Baltimore, Md.) - 1 Dec 2000
Jolley C D, Dietschy J M, Turley S D
Abstract excerpt
High density lipoprotein (HDL) cholesterol is believed to be preferentially utilized for bile acid synthesis and biliary secretion. In mice, the deletion of apolipoprotein AI (apo AI), the major apolipoprotein in HDL, results in very low plasma HDL-cholesterol levels. This article describes bile acid metabolism in apo AI-deficient (Apo AI(-/-)) mice and their C57BL/6 (Apo AI(+/+)) controls fed either a basal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.