Article
no-bridge and linotte act jointly at the interhemispheric junction to build up the adult central brain of Drosophila melanogaster.
Mechanisms of development - 1 Dec 2000
Hitier R, Simon A F, Savarit F, Préat T
Abstract excerpt
The Drosophila transmembrane protein Linotte (Lio) is expressed in a glial transcient interhemispheric fibrous ring (TIFR), which was hypothesised to serve as scaffold for adult brain formation during metamorphosis. We isolated TIFR specific enhancers from the lio locus and showed that only four interhemispheric cells give rise to this complex fibrous structure. We showed that lio controls the TIFR...
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