Article
T lymphocytes in asthma: bronchial versus peripheral responses.
The Journal of allergy and clinical immunology - 1 Nov 2000
Durham S R, Till S J, Corrigan C J
Abstract excerpt
Recent evidence points to the recruitment of T(H)2 cells, phenotype T lymphocytes, their activation, and the generation of T(H)2 cytokines, particularly IL-4 and IL-5, in both peripheral blood and bronchial mucosa of asthmatic patients, leading to local tissue eosinophilia and IgE-dependent mast-cell activation. Activation of T(H)2 T lymphocytes appears to be specific for asthma (as opposed to airway obstructive...
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