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Article

The Trophoblast Theory of Cancer (John Beard, 1857–1924) Revisited

9 Jun 2009

Abstract excerpt

Beard's theory can be restated in a modified form in modern terms in the following way. Cancer represents primarily trophoblastic tissue derived either from an aberrant germ cell or from a somatic cell whose normally repressed 'asexual generation' genes are abnormally reactivated ('derepressed'). The variety of tumors, other than teratomas, may be due to a parallel chance derepression of some genes of somatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1107920
DOI: 10.1159/000225037

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