Article
Maturation of IncP pilin precursors resembles the catalytic Dyad-like mechanism of leader peptidases.
Journal of bacteriology - 1 Dec 2000
Eisenbrandt R, Kalkum M, Lurz R, Lanka E
Abstract excerpt
The pilus subunit, the pilin, of conjugative IncP pili is encoded by the trbC gene. IncP pilin is composed of 78 amino acids forming a ring structure (R. Eisenbrandt, M. Kalkum, E.-M. Lai, C. I. Kado, and E. Lanka, J. Biol. Chem. 274:22548-22555, 1999). Three enzymes are involved in maturation of the pilin: LepB of Escherichia coli for signal peptide removal and a yet-unidentified protease for removal of 27...
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