Article
Lentivirus Nef specifically activates Pak2.
Journal of virology - 1 Dec 2000
Arora V K, Molina R P, Foster J L, Blakemore J L, Chernoff J, Fredericksen B L, Garcia J V
Abstract excerpt
Nef proteins from human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) have been found to associate with an active cellular serine/threonine kinase designated Nef-associated kinase (Nak). The exact identity of Nak remains controversial, with two recent studies indicating that Nak may be either Pak1 or Pak2. In this study, we investigated the hypothesis that such discrepancies arise...
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