Article
Replacement of tyr62 by trp in the designer protein milk bundle-1 results in significant improvement of conformational stability.
FEBS letters - 3 Nov 2000
Gagnon M C, Williams M, Doucet A, Beauregard M
Abstract excerpt
Protein design is currently used for the creation of new proteins with desirable traits. In our lab, we focus on the synthesis of proteins with high essential amino acid content, having potential application in animal nutrition. One of the limitations we face in this endeavor is the achievement of stable proteins in spite of a highly biased amino acid content. We report here the synthesis and characterization of...
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