Article
[Experimental resistance of Vibrio cholerae el tor to nalidixic acid and fluoroquinolones].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 2000
Ryzhko I V, Tsuraeva R I, Lomov Iu M, Shut'ko A G, Mishan'kin B N, Koroleva N S, Samokhodkina E D, Shcherbaniuk A I
Abstract excerpt
It was shown that sensitivity of Vibrio cholerae eltor P-5879 to tetracycline, levomycetin, furazolidone, trimethoprim/sulfamethoxazole, aminoglycosides, beta-lactams, rifampicin, quinolones in vitro correlated with drugs efficacy in the treatment of experimental cholera of albino mice. Mutants of V. cholerae eltor P-5879 Nalr resistant to nalidixic acid (MIC 160-200 mg/l) formed with frequency 10(-9)-110(-8) had...
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