Article
Population structure of rat-derived Pneumocystis carinii in Danish wild rats.
Applied and environmental microbiology - 1 Nov 2000
Palmer R J, Settnes O P, Lodal J, Wakefield A E
Abstract excerpt
The rat model of Pneumocystis carinii pneumonia is frequently used to study human P. carinii infection, but there are many differences between the rat and human infections. We studied naturally acquired P. carinii in wild rats to examine the relevance of the rat model for human infection. P. carinii DNA was detected in 47 of 51 wild rats and in 10 of 12 nonimmunosuppressed laboratory rats. Evidence for three...
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