Article
[Multiple endocrine neoplasia: a clinical model for applying molecular genetic techniques].
Revista medica de Chile - 1 Jul 2000
Wohllk N, Becker P, Véliz J, Pineda G
Abstract excerpt
Multiple endocrine neoplasias (MEN) are syndromes inherited as autosomal dominant. The application of the techniques of molecular biology has made possible the identification of the genes causing MEN 1 and 2. The gene responsible for MEN 1 belongs to the family of tumor suppressor genes and encodes for a protein named MENIN whose function remains to be elucidated. The identification of mutant MEN 1 gene carriers...
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