Article
[Genetics of multiple endocrine neoplasies: clinical implications].
Revue medicale suisse - 9 Feb 2005
Igaz P, Gaillard R C
Abstract excerpt
The multiple endocrine neoplasia (MEN) syndromes are hereditary monogenic diseases that are transmitted as autosomal dominant traits, and are characterized by the development of tumors and hyperplasias in several endocrine organs. The causative genes of the 2 principal forms of MEN have been recently identified; a protooncogene for MEN2 (the RET gene) and a tumor suppressor gene for MEN1 (the MEN1 gene)....
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